منابع مشابه
Stabilization of Proteins against Aggregation
Proteins degrade in vitro by a variety of routes, the most common of which is aggregation. In order to develop protein formulations that will limit aggregation, researchers use heuristic, experimental screening procedures. They do this because there is limited understanding of the mechanisms of aggregation and of the molecular-level effects of excipients (additives) on proteins and on protein r...
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The presence of a proximal cationic group in zwitterionic aryltrifluoroborates such as o-(Ph(2)MeP)C(6)H(4)(BF(3)) stabilizes these compounds against hydrolysis.
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We demonstrate that a recently published quasiclassical Møller type approach [Geyer and Rost 2002, J. Phys. B 35 1479] can be used to overcome the problem of autoionization, which arises in classical trajectory calculations for many electron targets. In this method the target is stabilized dynamically by a backward–forward propagation scheme. We illustrate this refocusing and present total cros...
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The Problem of Thermal Convection.-Electrophoresis presupposes the m ain tenance of an electric field in a conductive fluid (usually a buffer solution). The electric field dV/dx cannot be maintained without a concomitant current density J2 = u(dV/dx). In an electrophoretic column of uniform cross section, the heat generated in a unit volume per unit time will thus be: dQ/dt = Jxlla = (dV/dx)2a....
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Morphine dehydrogenase (MDH) of Pseudomonas putida M10 catalyses the NADP(+)-dependent oxidation of morphine and codeine to morphinone and codeinone. This enzyme forms the basis of a sensitive detection and assay method for heroin metabolites and a biotransformation process for production of hydromorphone and hydrocodone. To improve these processes we have undertaken a thorough examination of t...
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ژورنال
عنوان ژورنال: Stability: International Journal of Security and Development
سال: 2012
ISSN: 2165-2627
DOI: 10.5334/sta.ab